Saturday, October 18, 2014

Coenzyme Q10 Supplement for cardiovascular disease and high blood pressure

Coenzyme Q10 found and this year won from bovine heart mitochondria by Dr. Frederick Crane of the University of Wisconsin, USA 1957, Professor Morton of England also see the same thing from rat liver and there was ubiquinone. 1958, Professor Karl Folkers of Merck, Inc., is known that the chemical structure of the material: 2,3-dimethoxy-5-methyl-6-decaprenyl benzoquinone and the first to soCoenzyme Q10, also known as ubiquinone, ubidecarenone, coenzyme Q, and abbreviated at times to CoQ10/ˌkoʊ ˌkjuː ˈtɛn/, CoQ, or Q10 is a 1,4-benzoquinone, where Q refers to the quinone chemical group, and 10 refers to the number of isoprenyl chemical subunits in its tail.
Coenzyme Q10,Supplement  high blood pressure

This oil-soluble, vitamin-like substance is present in most eukaryotic cells, primarily in the mitochondria. It is a component of the electron transport chain and participates in aerobic cellular respiration, generating energy in the form of ATP. Ninety-five percent of the human body’s energy is generated this way.Therefore, those organs with the highest energy requirements—such as the heart, liver and kidney—have the highest CoQ10 concentrations.There are three redox states of CoQ10: fully oxidized (ubiquinone), semiquinone (ubisemiquinone), and fully reduced (ubiquinol). The capacity of this molecule to exist in a completely oxidized form and a completely reduced form enables it to perform its functions in the electron transport chain, and as an antioxidant, respectively.
lve the synthesis. In 1960, a Japanese scientist, Professor Yamamura is the first coenzyme Q7 (comes with Q10) used to treat heart failure. Mid-1970, the Japanese began producing this material in large quantities for clinical trials. Scientist Peter Mitchell was awarded the Nobel Prize for studies connected to indulge role w
ith this material. In other words, CoQ10 can compare the energy producers of the body. Due to these properties CoQ1o also has a significant effect on the reduction of migraine attacks. In fact one of the causes of migraine is the lack of energy in the cells of the brain. CoQ10 is also said to be able to reduce the blood pressure of 10 mm Hg during the 10 weeks of treatment.

whereas in patients with heart disease such as congestive heart failure, these supplements are quite helpful. This is because CoQ10 is found in a lot of heart cells that need a lot of power to pump 100,000 times a day without stopping. In addition, cholesterol-lowering drugs that are widely used cardiac patients, such as statins, which reduce the production of CoQ10 essential for cellular energy production of the heart. CoQ10 also has antioxidant effects and play a role in the treatment of Parkinson's disease when given in high doses. Therefore, there is a face cream that contains CoQ10 to slow the aging process. Several studies have also shown the benefits of CoQ10 in inhibiting the process of atherosclerosis, muscular dystrophy, breast cancer, diabetes mellitus, male infertility, Acquired Immune Deficiency Syndrome / AIDS, allergies, asthma, psoriasis, thyroid disorders, periodontal disease, Alzheimer's disease, and amyotrophic lateral sclerosis / ALS.

Source : Alternative Medicine Review 2007; 12:159-68. CoEnzyme Q10 (Ubiquinone) – Monograph. Bertram G. Katzung (Editor). Basic and Clinical Pharmacology 10th International Edition. Singapore: McGraw-Hill. 2007

No comments: